Publication J55650_EN, Instructions for Use, Blood Grouping Reagent Ortho Sera Anti-D(DVI) (Anti-RH1), Version 2.Donor and patient samples were tested in parallel with standard tests. Product Insert, Anti-A/B/A,B/D/CDE/Control Card, Revised January, 2015, Ortho Clinical Diagnostics, High Wycombe, Buckinghamshire/UK Ortho Clinical Diagnostics OrthoVision and Grifols Erytra Eflexis in 2018.Note that this new algorithm makes a 2+ reactivity with Anti-D/D7B8 as indeterminate. Used ORTHO-CLINICAL DIAGNOSTICS Johnson & Johnson Ortho PRO VUE Automated Hematology Analyzer Blood Bank System Blood Bank For Sale - DOTmed Listing.anti-D/D7B8 reactions 1, 2, mf, hemolyzed) ~ means any other value for that reagent (e.g.No reagents may be able to detect all D variants.Medinfo-Ortho interface settings for Blood Donor Center: Anti-D/D7B8 If the reaction is 2+ or less with the Ortho anti-D/D7B8 reagent or 1+ with either the CDE or DVI reagents is patterns 2, 3, 4, or 5 above, repeat by another manufacturer’s reagents, including DVI+ and DVI- sensitivities. Use the following table for interpretation and further actions if needed:ĭ-negative, probable rare genotypes r’ and/or r’’.For donors, run all three anti-D reagents listed- do not use the patient typing algorithm or reagents. the unique column agglutination technology (CAT) of the ORTHO BioVue system-considered the gold standard for manual and automated blood bank testing.If the D-control is positive, the reactions are indeterminate, repeat by another method.Follow the manufacturer’s instruction for storage, handling, and usage of all reagents.It does NOT detect Rh:33 (R 0 Har).Īnti-DVI/Anti-RH1 will agglutinate cells with a DVI phenotype, analogous to our previous DVI+ reagents. Most examples of partial D including DVI and weak D express C or E antigens and will be detected directly by the included anti-D or indirectly by the anti-C or anti-E in the cocktail. ![]() It may show different serologic activity compared to other D typing reagents.Īnti-CDE/Anti-RH1,2,3-IgM monoclonal blend of clone MS24 (anti-C), clone MAD2 (Anti-D), and clone C2 (Anti-E) can detect most cells expressing C, D, or E antigens. Retest positive reactions of 2+ or less by an alternate method. ![]() Ortho Diagnostics Reagents use three different monoclonal antibody cocktails that react variably with the antigen D (Rh1)-these are found on TWO (2) cards: Anti-A/B/A,B/D/CDE and Anti-DVI:Īnti-D/Anti-RH1-IgM monoclonal antibody clone D7B8 can detect most examples of weak and partial D including weak D types 1, 2, 3, 4.0, and D categories II, III, IV, V, VII, DBT, and R 0 Har. For the purpose of typing blood donors, we want to detect weak and partial D types and consider them as D-positive since even a portion of the D molecule is immunogenic and sensitization to it may cause anti-D hemolytic disease of the newborn.
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